19 Results for "

Poria cocos

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "Poria cocos" in MCE Product Catalog:

1
Poricoic acid A
Poricoic acid A
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1 Cited Publications
Art. -Nr.: HY-N2995
CAS. Nr.: 137551-38-3
Synonyms: Poricoic acid A(F)
Category:  

Triterpenes Terpenoids Polyporaceae Poria cocos Plants Disease Research Fields Cancer

Target:  

NF-κB Keap1-Nrf2 AMPK TGF-beta/Smad Reactive Oxygen Species (ROS)

Poricoic acid A can be isolated from Poria cocos. Poricoic acid A is an orally active anti-tumor agent. Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis. Poricoic acid A also attenuatea fibroblast activation and abnormal extracellular matrix remodeling in renal fibrosis by activating AMPK and inhibiting Smad3. Poricoic acid A significantly reduces the magnitude of rise in serum creatinine and urea levels in rat model when combined with Melatonin. Poricoic acid A ameliorates renal fibrosis and podocyte injury by attenuating oxidative stress and inflammation through regulating NF-κB and Nrf2 in IRI rodent model in combination with Melatonin .
L-Uridine
L-Uridine
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Art. -Nr.: HY-W006429
CAS. Nr.: 26287-69-4
Category:  

Natural Products Polyporaceae Metabolic Disease Poria cocos Plants Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

L-Uridine is an enantiomer of the normal RNA constituent D-uridine. L-Uridine can be isolated from the Polyporaceae fungus Poria cocos (Schw.). L-uridine acts as a phosphate acceptor for nucleoside phosphotransferases .
Polyporenic acid C
Polyporenic acid C
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Art. -Nr.: HY-N2993
CAS. Nr.: 465-18-9
Category:  

Triterpenes Terpenoids Polyporaceae Poria cocos Plants Disease Research Fields Cancer

Target:  

Apoptosis Caspase PARP Akt PTEN MDM-2/p53 JNK

Polyporenic acid C is a lanostane-type triterpenoid. Polyporenic acid C can be isolated from Poria cocos. Polyporenic acid C causes the cleavage of caspase-8 and caspase-3, as well as the cleavage of PARP. Polyporenic acid C reduces the phosphorylation level of Akt (Ser473), increases the phosphorylation of PTEN and p53 (Ser15), and activates JNK. Polyporenic acid C induces Apoptosis. Polyporenic acid C shows anticancer activity against non-small cell lung cancer .
Dehydrotumulosic acid
Dehydrotumulosic acid
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Art. -Nr.: HY-N2499
CAS. Nr.: 6754-16-1
Category:  

Triterpenes Terpenoids Polyporaceae Metabolic Disease Poria cocos Plants Disease Research Fields

Target:  

Others

Dehydrotumulosic acid is one of the effective constituents of Poria cocos. Poria cocos, a popular Chinese medicinal herb of fungal origin, has been included in many combinations with other CM herbs for its traditionally claimed activities of inducing diuresis, excreting dampness, invigorating the spleen and tranquilizing the mind and its modern pharmacological use of modulating the immune system of the body .
Poricoic acid B
Poricoic acid B
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Art. -Nr.: HY-N4124
CAS. Nr.: 137551-39-4
Category:  

Triterpenes Terpenoids Polyporaceae Poria cocos Plants Disease Research Fields Cancer

Target:  

NO Synthase TNF Receptor Interleukin Related

Poricoic acid B is a triterpenoid compound that can be isolated from Poria cocos. Poricoic acid B inhibits intracellular lipid accumulation and reduces the levels of hepatocyte injury markers. Poricoic acid B inhibits the production of NO, TNF-α, IL-1β and IL-6, thereby exerting anti-inflammatory activity. Poricoic acid B can be used in the research of metabolic dysfunction-associated fatty liver disease and inflammatory diseases [3].
16α-Hydroxydehydrotrametenolic acid
16α-Hydroxydehydrotrametenolic acid
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Art. -Nr.: HY-N2990
CAS. Nr.: 176390-66-2
Synonyms: 3β,16α-Dihydroxylanosta-7,9(11),24-trien-21-oic acid
Category:  

Triterpenes Terpenoids Polyporaceae Poria cocos Plants Disease Research Fields Inflammation/Immunology

Target:  

Others

16α-Hydroxydehydrotrametenolic acid is a triterpene Acid in fermented mycelia of edible fungus Poria cocos .
Dehydropachymic acid
Dehydropachymic acid
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Art. -Nr.: HY-N2991
CAS. Nr.: 77012-31-8
Category:  

Triterpenes Terpenoids Polyporaceae Poria cocos Plants

Target:  

Autophagy

Dehydropachymic acid is one of the major triterpenes isolated from Poria cocos. Dehydropachymic acid is more effective in autophagy-lysosome pathway (ALP) impaired cells rather than normal cells .
3-Dehydrotrametenolic acid
3-Dehydrotrametenolic acid
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Art. -Nr.: HY-N2177
CAS. Nr.: 29220-16-4
Category:  

Triterpenes Terpenoids Polyporaceae Poria cocos Plants Disease Research Fields Cancer

Target:  

Lactate Dehydrogenase Apoptosis

3-​Dehydrotrametenolic acid, isolated from the sclerotium of Poria cocos, is a lactate dehydrogenase (LDH) inhibitor. 3-​Dehydrotrametenolic acid promotes adipocyte differentiation in vitro and acts as an insulin sensitizer in vivo. 3-​Dehydrotrametenolic acid induces apoptosis and has anticancer activity .
3-O-Acetyl-16α-hydroxytrametenolic acid
3-O-Acetyl-16α-hydroxytrametenolic acid
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Art. -Nr.: HY-N2994
CAS. Nr.: 168293-13-8
Category:  

Triterpenes Terpenoids Polyporaceae Poria cocos Plants Disease Research Fields Cancer

Target:  

Others

3-O-Acetyl-16α-hydroxytrametenolic acid (Compound 3) is a triterpene found in Poria cocos, with anti-oxidant and anti-cancer activity .
Dehydrotrametenolic acid
Dehydrotrametenolic acid
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Art. -Nr.: HY-N2490
CAS. Nr.: 6879-05-6
Category:  

Triterpenes Terpenoids Polyporaceae Poria cocos Plants Disease Research Fields Inflammation/Immunology

Target:  

Caspase Apoptosis

Dehydrotrametenolic acid is a sterol isolated from the sclerotium of Poria cocos. Dehydrotrametenolic acid induces apoptosis through caspase-3 pathway. Dehydrotrametenolic acid has anti-tumor activity, anti-inflammatory, anti-diabetic effects .
3-O-beta-Allopyranosyl-(1->4)-beta-oleandropyranosyl-11-O-isobutyryl-12-O-acetyltenacigenin B
3-O-beta-Allopyranosyl-(1->4)-beta-oleandropyranosyl-11-O-isobutyryl-12-O-acetyltenacigenin B
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Art. -Nr.: HY-N2142
CAS. Nr.: 1260252-18-3
Category:  

Polyporaceae Poria cocos Plants Disease Research Fields Cancer Steroids

Target:  

Others

3-O-beta-Allopyranosyl-(1->4)-beta-oleandropyranosyl-11-O-isobutyryl-12-O-acetyltenacigenin B is a chemical constituent of the plant Poria cocos .
Poria cocos extract
Poria cocos extract
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Art. -Nr.: HY-N18767
CAS. Nr.: 168456-53-9
Category:  

Extract

Target:  

Others

Poria Cocos Extract is obtained from the dried sclerotia of the fungus Poria cocos. It has a variety of skin care effects and is widely used in functional cosmetics.
Dehydrotumulosic acid (Standard)
Dehydrotumulosic acid (Standard)
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Art. -Nr.: HY-N2499R
CAS. Nr.: 6754-16-1
Category:  

Triterpenes Terpenoids Polyporaceae Poria cocos Plants

Target:  

Reference Standards Others

Dehydrotumulosic acid (Standard) is the analytical standard of Dehydrotumulosic acid. This product is intended for research and analytical applications. Dehydrotumulosic acid is one of the effective constituents of Poria cocos. Poria cocos, a popular Chinese medicinal herb of fungal origin, has been included in many combinations with other CM herbs for its traditionally claimed activities of inducing diuresis, excreting dampness, invigorating the spleen and tranquilizing the mind and its modern pharmacological use of modulating the immune system of the body .
Poricoic acid G
Poricoic acid G
0 Images
Art. -Nr.: HY-N10071
CAS. Nr.: 415724-84-4
Category:  

Microorganisms Ketones, Aldehydes, Acids

Target:  

Others

Poricoic acid G is a triterpenoid that can be isolated from Poria cocos. Poricoic acid G has a significant cytotoxic effect on leukemia cells and is a potential potent anti-leukemic compound in humans .
3β-Acetoxy-5α-lanosta-8,24-dien-21-oic acid
3β-Acetoxy-5α-lanosta-8,24-dien-21-oic acid
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Art. -Nr.: HY-N13070
CAS. Nr.: 117895-68-8
Category:  

Triterpenes Microorganisms Terpenoids

Target:  

Others

3β-Acetoxy-5α-lanosta-8,24-dien-21-oic acid (compound 89) can be isolated from the secretions of the fungus Poria cocos (Schw.) .
Dehydropachymic acid (Standard)
Dehydropachymic acid (Standard)
0 Images
Art. -Nr.: HY-N2991R
CAS. Nr.: 77012-31-8
Category:  

Triterpenes Terpenoids Polyporaceae Poria cocos Plants

Target:  

Reference Standards Autophagy

Dehydropachymic acid (Standard) is the analytical standard of Dehydropachymic acid. This product is intended for research and analytical applications. Dehydropachymic acid is one of the major triterpenes isolated from Poria cocos. Dehydropachymic acid is more effective in autophagy-lysosome pathway (ALP) impaired cells rather than normal cells .
Polyporenic acid C (Standard)
Polyporenic acid C (Standard)
0 Images
Art. -Nr.: HY-N2993R
CAS. Nr.: 465-18-9
Category:  

Triterpenes Terpenoids Polyporaceae Poria cocos Plants

Target:  

Reference Standards Apoptosis Caspase PARP Akt PTEN MDM-2/p53 JNK

Polyporenic acid C (Standard) is an analytical standard of Polyporenic acid C (HY-N2993). This product is intended for research and analytical applications. Polyporenic acid C is a lanostane-type triterpenoid. Polyporenic acid C can be isolated from Poria cocos. Polyporenic acid C causes the cleavage of caspase-8 and caspase-3, as well as the cleavage of PARP. Polyporenic acid C reduces the phosphorylation level of Akt (Ser473), increases the phosphorylation of PTEN and p53 (Ser15), and activates JNK. Polyporenic acid C induces Apoptosis. Polyporenic acid C shows anticancer activity against non-small cell lung cancer .
Poricoic acid AE
Poricoic acid AE
0 Images
Art. -Nr.: HY-N8978
CAS. Nr.: 1159753-88-4
Category:  

Triterpenes Microorganisms Terpenoids

Target:  

Drug Derivative

Poricoic acid AE is a natural triterpene.
L-Uridine (Standard)
L-Uridine (Standard)
0 Images
Art. -Nr.: HY-W006429R
CAS. Nr.: 26287-69-4
Category:  

Natural Products Polyporaceae Poria cocos Plants Endogenous metabolite

Target:  

Endogenous Metabolite Reference Standards

L-Uridine (Standard) is the analytical standard of L-Uridine (HY-W006429). This product is intended for research and analytical applications. L-Uridine is an enantiomer of the normal RNA constituent D-uridine. L-Uridine can be isolated from the Polyporaceae fungus Poria cocos (Schw.). L-uridine acts as a phosphate acceptor for nucleoside phosphotransferases .
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